Parkinson's disease (PD) research aims to understand the causes, mechanisms, and potential treatments for this neurodegenerative disorder.

Areas of Research:

• Genetics: Identifying genetic mutations that increase the risk of PD.

• Neurobiology: Studying the changes in brain cells and pathways that occur in PD.

• Cell Death: Investigating why dopamine-producing neurons die in PD.

• Oxidative Stress: Examining the role of oxidative damage in the disease process.

• Mitochondrial Dysfunction: Exploring how impaired mitochondrial function contributes to PD.

• Stem Cell Therapy: Using stem cells to replace damaged neurons or to protect existing ones.

• Gene Therapy: Developing genetic interventions to stop or slow the progression of PD.

• Drug Discovery: Identifying and testing new medications to improve symptoms and potentially halt disease progression.

Leading Research Institutions: National Institute of Neurological Disorders and Stroke (NINDS), Parkinson's Foundation, Michael J. Fox Foundation for Parkinson's Research, Harvard Stem Cell Institute, and University of Miami Miller School of Medicine.

Fox Trial Finder: Find Parkinson's Clinical Trials

https://www.michaeljfox.org/trial-finder

Search to find studies based on your location and health history. No login is required. Want to be notified when new studies match your profile? Sign up today.

Read an overview on Fox Trial Finder and its new features. If you have questions or if you'd like help, please email support@foxtrialfinder.org.

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ClinicalTrials.gov:

• A comprehensive, public registry of federally and privately supported clinical trials.

• Enables searches using keywords, locations, and specific disease, such as "Parkinson's disease".

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• Parkinson's Foundation Clinical Trials Page:

  • .Provides resources and links to studies, including genetic-specific trials like thePD GENEration study

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