Category Archives: Parkinson’s in the news

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Parkinson’s patients could be cured of tremors using new ultrasound machine

Parkinson’s patients and others suffering debilitating tremors could be cured of their shaking using a new ultrasound machine which targets their brain cellsDoctors at Imperial College Healthcare NHS Trust have treated the first patients using the new technique which avoids the need for invasive brain surgery.
Read more 


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Parkinson’s could be treated with shark compound?

Squalamine, a chemical compound found in dogfish sharks, has the potential to reduce the formation of toxic proteins related to the development of Parkinson’s disease, new research suggests

Published in the Proceedings of the National Academy of Sciences, the study reveals that squalamine halted the buildup and toxicity of the protein alpha-synuclein (α-synuclein) in roundworm models of Parkinson’s disease and human neuronal cells.

Read more http://www.telegraph.co.uk/science/2017/01/16/dogfish-shark-extract-could-help-treat-parkinsons-disease-scientists/


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Diabetes drug slows experimental Parkinson’s disease progression, human trials to begin next year

A new investigational drug originally developed for type 2 diabetes is being readied for human clinical trials in search of the world’s first treatment to impede the progression of Parkinson’s disease, following publication of research findings today in the journal Science Translational Medicine. More

A drug initially designed to treat diabetes may be a breakthrough treatment for Parkinson’s disease. After decades of disappointment, could MSDC-0160 be the drug researchers have been searching for? More


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Common Natural Sweetener May Treat Parkinson’s Disease

This post is about experimental drugs and treatments, Under absolutely no circumstances should anyone reading this consider it medical advice.  These are novel results that need to be replicated and verified before being considered gospel.  Before considering or attempting any change in your treatment regime, please consult with your doctor or neurologist. 

The natural sweetener mannitol, a common component of sugar-free gums and candies, may hold potential for Parkinson’s disease (PD) according to a study, funded in part by the Parkinson’s Disease Foundation, in the June 14, 2013  issue of The Journal of Biological Chemistry. In this initial study, the compound not only improved PD-like symptoms in fruit flies, but also reduced harmful levels of alpha-synuclein (the hallmark of PD) in the brains of fruit flies and mice.

Read more at http://www.pdf.org/en/science_news/release/pr_1373476667


The Israeli scientists were interested in the ability of Mannitol to inhibit the formation of alpha synuclein aggregates (clumps of the protein that is associated with Parkinson’s disease). Chemicals similar to Mannitol have exhibited protein destabilizing properties, so it was an interesting idea to test.

The researchers used different concentrations of mannitol and added it to a solution of alpha-synuclein. They left this concoction shaking for 6 days (at 37°C) and then assessed the levels of aggregation. Curiously the low levels of Mannitol had the strongest inhibitory effect, while the higher concentrations had no effect. The researchers repeated the experiments and found similar results.

Given this success, they turned their attention to an animal model of alpha synuclein: a genetically engineered fly that produces a lot of alpha synuclein. They found that Mannitol treated flies had significantly less alpha synuclein aggregation in their brain than untreated flies. This study was then repeated in genetically engineered mice (that produce too much alpha synuclein) and guess what? They found the same results.

These results led the scientists to suggest that “mannitol administration in combination with other drugs could be a promising new approach for treating PD and other brain-related diseases such as Alzheimer disease”.

A warning regarding Mannitol

Before you rush out and start loading up on Mannitol there are a few things you should know about it.

It is used medically, usually to treat increased pressure within the skull.

It should not be abused, however, as it can have an osmotic effect (in particular, attracting water from the intestinal wall). Consumed in excess, it will cause diarrhea, abdominal pain, and excessive gas.

In addition to intestinal problems, Mannitol has also been associated with worsening heart failure, electrolyte abnormalities, or low blood volume. We also do not know what effect it may have on absorption of L-dopa and other Parkinson’s disease medications.

Read more at https://scienceofparkinsons.com/2016/05/10/manna-from-heaven-mannitol-and-parkinsons-disease/


Tel Aviv University researchers say artificial sweetener could prevent aggregation of toxic proteins in the brain.
http://mfa.gov.il/MFA/InnovativeIsrael/ScienceTech/Pages/Sweet-news-for-Parkinson’s-disease-4-May-2014.aspx


Another Possible Benefit of Taking Mannitol for Parkinson’s

An added benefit, it has the effect of stimulating a daily bowel movement. If someone is looking for assistance with constipation mannitol can serve double duty!!


Listen to the radio show interview with Don Don McCammon which I have embedded in this post below.

http://www.medscape.com/viewarticle/806873

Mannitol would be an attractive treatment option because it’s already approved for various medical uses by the FDA, as a diuretic and as a rinsing agent during certain surgical procedures.


Testimonials

 


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Blocking brain enzyme corrects motor symptoms in mice

New drug research shows promising results in mice bred to develop the motor symptoms of Parkinson’s disease. A team in Finland finds that blocking an enzyme called prolyl oligopeptidase clears the mice’s brains of an accumulated protein that is a hallmark of Parkinson’s disease, halts further brain damage, and corrects movement impairment.

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Timing may be key to understanding cognitive problems in Parkinson’s disease

Brain stimulation replaces missing brain wave and improves cognitive process in mice that lack dopamine

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Microsoft researcher creates wearable which smooths handwriting in Parkinson’s Disease

Haiyan Zhang, Innovation Director at Microsoft Research Cambridge, has taken part in the BBC’s The Big Life Fix challenge which asks young technologists to use their skills to help others.
Her task was to find a way to help 29-year-old Emma Lawton, who is a graphics designer, to improve her writing and drawing skills after this was negatively impacted by her Parkinson’s Disease diagnosed three years ago.

Read more at BBC.com

Read more at steemit.com

(Video) Emotional moment young woman with Parkinson’s Disease writes again thanks to gadget read more at mirror.co.uk


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2016 Parkinson’s holiday gift guide

The holiday season has arrived and although it’s an exciting time, it can be a bit stressful to find that perfect gift for your favorite Parkie.

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What Does the Election Mean for the Parkinson’s Community?

As a new president takes office next year, the political environment in Washington, DC, will change.

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Parkinson’s News Today – social clips

See short, informative clips from Parkinson’s News Today

These and more…

Parkinson’s Quote: Look Beyond Imperfections

When you have Parkinson’s disease sometimes you feel imperfect.

Maya Angelou once said, “Being happy doesn’t mean that everything is perfect. It means that you’ve decided to look beyond the imperfections.


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Janet Reno

Not even Parkinson’s disease has slowed the former Attorney General’s life on the move

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Stem Cell Transplants 

The first transplantation of stem cells in patients with Parkinson’s disease is almost within reach.  

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FMP initiates new project for early detection of Parkinson’s disease with magnetized xenon gas

A new project for the early detection of Parkinson’s disease with strongly magnetized xenon gas has been initiated at FMP. The team led by physicist Leif Schröder has received a three-year grant from the Michael J. Fox Foundation for Parkinson’s Research. Read more


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Data on Parkinson’s disease therapy CVT-301 published in Science Translational Medicine

Results from Phase 1, Phase 2a and preclinical studies of CVT-301, an inhaled form of levodopa, have been featured in the current edition of Science Translational Medicine. Acorda Therapeutics, Inc. (NASDAQ: ACOR) is developing CVT-301 for the treatment of OFF periods in people with Parkinson’s disease (PD).

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World Parkinson’s Congress 2016

The triennial World Parkinson Congresses provide an international forum for dialogue on the latest scientific discoveries, medical practices, and caregiver initiatives related to Parkinson’s disease.

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Coffee is your friend

coffee-beans-1400Caffeine-based compounds show promise against Parkinson’s disease

Two caffeine-based chemical compounds have been developed that show promise in preventing the ravages of Parkinson’s disease. Parkinson’s disease attacks the nervous system, causing uncontrolled shakes, muscle stiffness, and slow, imprecise movement, chiefly in middle-aged and elderly people. It is caused by the loss of brain cells (neurons) that produce dopamine, an essential neurotransmitter that allows neurons to “talk” to each other.

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AFrFiRiS AG Parkinsons vaccine

VIENNA, Austria, September 07, 2016 — AFrFiRiS AG announced today results of AFF008A,

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New levodopa ‘inhaler’ designed to eliminate ‘off’ times

An inhaled form of levodopa is being trialled on Parkinson’s disease patients in a Phase III clinical trial at the University of Nevada School of Medicine.

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Google News for Parkinson’s

Did you know you can tell Google to send an e-mail to yourself with search results of your choice?

I get one a week with the results of finding the words “Parkinson’s Disease” in the news

How to Create an alert

  1. Visit Google Alerts.
  2. In the “Create an alert about” box, enter the words you want to get email notifications for.
  3. Click Show options to say how often you get alerts, what types of results you want to get, and more.
  4. Click Create Alert.
  5. Once your alert is set up, you’ll start getting emails any time we find new search results for your keywords.

Google News for Parkinson’s


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Parkinson’s Wellness Recovery Class @ Clifton Park YMCA
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PWR – Parkinson’s Wellness Recovery Class Thursdays 10:30 – 11:45 Cost $45 for 7 weeks – Clifton Park YMCA – 1 Wall Street, Clifton Park, NY 12065 – Phone (518) 371-2139 Contact the Y for
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1:45 pm Parkinson’s Dance Syracuse @ Dance Theater of Syracuse
Parkinson’s Dance Syracuse @ Dance Theater of Syracuse
Mar 23 @ 1:45 pm – 3:00 pm
Parkinson’s Dance (re-defining PD) Thursdays 1:30-2:45 pm Weekly Drop-ins welcome No charge Lead teacher: Tumay Tunur Dance styles/techniques/content covered in class: Ballet, Tap, Contemporary, Latin, Improvisation Dance Theater of Syracuse 117 Harvard Place Syracuse, NY
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10:00 am Schott’s Boxing @ Schott's Boxing
Schott’s Boxing @ Schott's Boxing
Mar 24 @ 10:00 am – 11:00 am
Every Friday at 10 This program was started in 2016 by Hope Soars and Schott’s Boxing and Fitness to enhance the quality of life of the Parkinson’s patient. There is a direct correlation between the
10:30 am P4P Troy YMCA @ Troy YMCA
P4P Troy YMCA @ Troy YMCA
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PEDALING FOR PARKINSON’S Pedaling a bicycle may change the life  of someone with Parkinson’s disease. Research conducted at the Cleveland Clinic showed a 35% reduction in symptoms by the simple act of pedaling a bicycle
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P4P Clifton Park YMCA @ Clifton Park YMCA
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The mission of Pedaling for Parkinson’s is: To improve the quality of life of Parkinson’s disease patients and their caregivers. To educate patients, caregivers, and the general public about the benefits of maintaining an active