A recent article in the Harvard Gazette suggests dance as a potential treatment for neurodegenerative disorders such as Parkinson’s disease (PD).
Imaging studies have identified several brain regions involved in the complex, rhythmical, and coordinated movements that constitute dance. The motor cortex is — as with other kinds of voluntary movement — involved in planning, controlling, and executing dance moves.
32 Minute video from Davis Phinney Foundation
Prepare for Your Hospital Stay Worksheet — Information regarding medications, symptoms and advanced directives in preparation for your hospital stay. Also included is a list of what to inform, ask and know during your hospitalization.
By The Michael J. Fox Foundation for Parkinson’s ResearchDo you know anyone who has Parkinson’s disease (PD)? It’s likely – the neurodegenerative disease affects one in 100 people over the age of 60, and more than 5 million people worldwide. Today, medicines exist to alleviate motor symptoms of the disease, but currently there are no treatments that can slow or stop its progression.
Researchers believe Parkinson’s results from a combination of both genetic and environmental factors, and, in recent years, scientists have discovered a number of genetic mutations associated with Parkinson’s. In about one percent of PD cases, the disease can be linked to a mutation in a gene called LRRK2.
While that may sound like a small number, the percentage is much higher in certain populations. In the Ashkenazi Jewish population, the mutation is responsible for 15 to 20 percent of PD cases. It is important to note that not everyone with a LRRK2 mutation will go on to develop Parkinson’s. But researchers believe that learning more about the genetics of Parkinson’s by studying those with and without the disease can help drive progress toward new treatments for everyone with PD.
A global study called the Parkinson’s Progression Markers Initiative (PPMI) launched efforts earlier this year to learn more about the genetics of PD. Families that carry a LRRK2 mutation have a vital role to play in this study, and there’s an easy way to be involved. The study is seeking volunteers to complete a brief survey to determine if they may be eligible to receive genetic counseling and testing of the LRRK2 gene at no cost.
Take the survey to see if you qualify
By and large, Parkinson’s has not been considered to be a genetic disease. The majority of cases are called idiopathic, which simply means that we don’t know what caused the disease. In fact, only about 10 percent of PD cases have been linked to a genetic cause. Mutations in the LRRK2 gene are the most common cause of PD in this relatively small group, representing one to two percent of total Parkinson’s cases.
However, for people of certain ethnic backgrounds — Ashkenazi Jewish, North African Arab Berbers and Basque — mutations in LRRK2 account for a much greater number of PD cases than in the general population. While estimates vary, it is believed that changes in LRRK2 (predominantly the mutation scientists know as G2019S) account for 15 to 20 percent of cases in Ashkenazi Jews and about 40 percent of cases in North African Arab Berbers. Other genetic changes in LRRK2 that increase the risk of Parkinson’s disease have been found in additional populations, such as in Asians of Chinese descent. It remains an active area of research to find all the genetic changes in LRRK2 that may lead to Parkinson’s disease.
do you want to participate in a sty study?
click here https://www.michaeljfox.org/page.html?ppmi-genetics
Measuring a particular blood protein might help doctors easily distinguish Parkinson’s disease from some similar disorders, a new study suggests.
The potential blood test is “not ready for prime time,” Parkinson’s disease experts said. But, it marks progress in the quest for an objective way to diagnose Parkinson’s and similar conditions known as atypical parkinsonian disorders, they noted.
Life expectancy for people with Parkinson’s who receive proper treatment is often about the same as for the general population. Early detection is the key to reducing complications that can shorten your life. If you suspect that you or a loved one may have Parkinson’s disease, see your doctor right away.
Please call 518-262-0739 to reserve your spot!
BASIC TANGO WORKSHOP
And you’re invited March 29th at 12 Noon!
Presented by: Kevin Magee Albany Tango Society and Meghan Wilock PA
Where: The Desmond, 660 Albany Shaker Rd Albany, NY 12211
When: 3/29/17 at 12PM-2:00PM
Kevin Magee is the organizer and founder of the Albany Tango Society, presenting tango events in Albany since 2007. Through Albany Tango Society Kevin teaches four levels of tango instruction, beginners to advanced, and presents free weekly classes to the community. As an organizer and presenter, Kevin has hosted over four hundred guest artist visits to the Capital Region, drawing from the top echelon of tango dancers world-wide. Kevin is an instructor at Emma Willard School (Troy, NY) teaching ballet, modern dance and jazz dance. He also teaches tango through the Student Union at Rensselaer Polytechnic Institute (Troy, NY) and at SUNY, Albany.
We welcome all to the support group, those with DBS (Deep Brain Stimulation), considering DBS, Parkinson’s disease, Dystonia, or Essential Tremor. We also encourage family and friends to join as well.
See you there
Parkinson’s patients and others suffering debilitating tremors could be cured of their shaking using a new ultrasound machine which targets their brain cellsDoctors at Imperial College Healthcare NHS Trust have treated the first patients using the new technique which avoids the need for invasive brain surgery.
Squalamine, a chemical compound found in dogfish sharks, has the potential to reduce the formation of toxic proteins related to the development of Parkinson’s disease, new research suggests
Published in the Proceedings of the National Academy of Sciences, the study reveals that squalamine halted the buildup and toxicity of the protein alpha-synuclein (α-synuclein) in roundworm models of Parkinson’s disease and human neuronal cells.
Read more http://www.telegraph.co.uk/science/2017/01/16/dogfish-shark-extract-could-help-treat-parkinsons-disease-scientists/
The 100 trillion or so bacteria in our guts are important players in our normal biological processes and in protection against disease. Researchers have begun exploring possible imbalances in some bacteria levels in people with Parkinson’s and how those differences may lead to disease onset or progression. While this area of investigation is still fairly new, the field has some promising leads.
Vitamin B3 (niacin) was found to boost levels of a compound called NAD that generates energy and repairs DNA, according to new research that suggests boosting Vitamin B3 could keep Parkinson’s disease (PD) at bay.
Parkinson’s declines slowly, and not over hours, days or weeks. If PD symptoms worsen precipitously over a short period of time, then it is critical to search for secondary causes for these worsening symptoms. Potential causes for worsening Parkinson’s symptoms may include medication changes (which may be intentional changes or due to medication error), infections (such as a urinary tract infection, cold or flu), other medical problems (e.g., dehydration, problems with the heart, lungs, kidneys, liver, etc.), and/or stress, sleep deprivation, etc. read more http://www.pdf.org/en/parkinson_briefing_secrets_myths_question_answer
The National Parkinson Foundation (NPF) runs a toll-free Helpline, 1-800-4PD-INFO, (473-4636) The lifesaving NPF Helpline, launched in 2010, is staffed by a team of patient-focused nurses, social workers and therapists who answer calls about Parkinson’s disease (PD) in English and in Spanish Monday through Friday from 9 a.m. to 5 p.m. EST.
“NPF’s Helpline links our groundbreaking research to improve the lives of people with Parkinson’s today directly with the community we serve,” I know this first hand because the Helpline has made a difference in the life of my mother, who is living with Parkinson’s.” –John Kozyak, NPF’s Chairman of the Board. ”
“We’re more than just an information line. We truly care about the people we serve and that’s the key to our success, Whether you have yet to receive a diagnosis, are recently diagnosed with Parkinson’s, or caring for a family member with the disease, we are here to help you understand your condition, your care, and the latest research on how patients can live their best lives with Parkinson’s. We spend as much as 45 minutes on calls with those who have been recently diagnosed – more than three times the average – because we can really make a difference.” – Adolfo Diaz, NPF’s Director of Patient Services who manages the Helpline.”
NPF’s Helpline Specialists help callers locate resources in their area, as well as send a customized informational packet after the call. The NPF packets arm people with Parkinson’s and their families with helpful information on preparing for an appointment with their general practitioner or movement disorder specialist. People with Parkinson’s disease, their care partners and families are invited to call to receive emotional support and referrals to health professionals and community resources. A wide variety of helpful NPF publications and the Aware in Care kit are also available for order through the Helpline.
NPF also has an online video series called, “Ask the Helpline,” where our PD Specialists answer the most frequently asked questions including: why exercise is important, what role a movement disorder specialist plays and how the role of caregiver changes over time.
People with questions about PD may also e-mail the NPF Helpline at email@example.com.
A new investigational drug originally developed for type 2 diabetes is being readied for human clinical trials in search of the world’s first treatment to impede the progression of Parkinson’s disease, following publication of research findings today in the journal Science Translational Medicine. More
A drug initially designed to treat diabetes may be a breakthrough treatment for Parkinson’s disease. After decades of disappointment, could MSDC-0160 be the drug researchers have been searching for? More
This post is about experimental drugs and treatments, Under absolutely no circumstances should anyone reading this consider it medical advice. These are novel results that need to be replicated and verified before being considered gospel. Before considering or attempting any change in your treatment regime, please consult with your doctor or neurologist.
The natural sweetener mannitol, a common component of sugar-free gums and candies, may hold potential for Parkinson’s disease (PD) according to a study, funded in part by the Parkinson’s Disease Foundation, in the June 14, 2013 issue of The Journal of Biological Chemistry. In this initial study, the compound not only improved PD-like symptoms in fruit flies, but also reduced harmful levels of alpha-synuclein (the hallmark of PD) in the brains of fruit flies and mice.
The Israeli scientists were interested in the ability of Mannitol to inhibit the formation of alpha synuclein aggregates (clumps of the protein that is associated with Parkinson’s disease). Chemicals similar to Mannitol have exhibited protein destabilizing properties, so it was an interesting idea to test.
The researchers used different concentrations of mannitol and added it to a solution of alpha-synuclein. They left this concoction shaking for 6 days (at 37°C) and then assessed the levels of aggregation. Curiously the low levels of Mannitol had the strongest inhibitory effect, while the higher concentrations had no effect. The researchers repeated the experiments and found similar results.
Given this success, they turned their attention to an animal model of alpha synuclein: a genetically engineered fly that produces a lot of alpha synuclein. They found that Mannitol treated flies had significantly less alpha synuclein aggregation in their brain than untreated flies. This study was then repeated in genetically engineered mice (that produce too much alpha synuclein) and guess what? They found the same results.
These results led the scientists to suggest that “mannitol administration in combination with other drugs could be a promising new approach for treating PD and other brain-related diseases such as Alzheimer disease”.
A warning regarding Mannitol
Before you rush out and start loading up on Mannitol there are a few things you should know about it.
It is used medically, usually to treat increased pressure within the skull.
It should not be abused, however, as it can have an osmotic effect (in particular, attracting water from the intestinal wall). Consumed in excess, it will cause diarrhea, abdominal pain, and excessive gas.
In addition to intestinal problems, Mannitol has also been associated with worsening heart failure, electrolyte abnormalities, or low blood volume. We also do not know what effect it may have on absorption of L-dopa and other Parkinson’s disease medications.
Tel Aviv University researchers say artificial sweetener could prevent aggregation of toxic proteins in the brain.
Another Possible Benefit of Taking Mannitol for Parkinson’s
An added benefit, it has the effect of stimulating a daily bowel movement. If someone is looking for assistance with constipation mannitol can serve double duty!!
Listen to the radio show interview with Don Don McCammon which I have embedded in this post below.
Mannitol would be an attractive treatment option because it’s already approved for various medical uses by the FDA, as a diuretic and as a rinsing agent during certain surgical procedures.
Haiyan Zhang, Innovation Director at Microsoft Research Cambridge, has taken part in the BBC’s The Big Life Fix challenge which asks young technologists to use their skills to help others.
Her task was to find a way to help 29-year-old Emma Lawton, who is a graphics designer, to improve her writing and drawing skills after this was negatively impacted by her Parkinson’s Disease diagnosed three years ago.
Read more at BBC.com
Read more at steemit.com
(Video) Emotional moment young woman with Parkinson’s Disease writes again thanks to gadget read more at mirror.co.uk
Whatever movement of the wrist is performed, the bowl of the spoon remains horizontal and keeps the food in place.
The material used is lightweight and strong. A key characteristic is the spoon’s affordability.
There are no electrical components or batteries, making it carry anywhere and to clean.
ELISPOON is a product designed and built to ease the life of the users and their love.
Two graduates from Israel’s Technion developed a spoon that their child with motor co-ordination problems could use without spilling its contents. Now anyone can buy it. Useful also for the elderly or anyone suffering from tremor
An Internet forum is a discussion area on a website. Website members can post discussions and read and respond to posts by other forum members. A forum can be focused on nearly any subject and a sense of an online community, or virtual community, tends to develop among forum members. A forum usually allows all members to make posts and start new topics.
Recent advances in neuroscience have suggested that exercise-based behavioral treatments may improve function and possibly slow progression of motor symptoms in individuals with Parkinson disease (PD). The LSVT (Lee Silverman Voice Treatment) Programs for individuals with PD have been developed and researched over the past 20 years beginning with a focus on the speech motor system (LSVT LOUD) and more recently have been extended to address limb motor systems (LSVT BIG).
A new drug for levodopa-induced dyskinesia — involuntary, uncontrolled movements that can develop with long-term use of levodopa combined with a prolonged course of Parkinson’s disease (PD) — is one step closer to potentially reaching market.
A new project for the early detection of Parkinson’s disease with strongly magnetized xenon gas has been initiated at FMP. The team led by physicist Leif Schröder has received a three-year grant from the Michael J. Fox Foundation for Parkinson’s Research. Read more
Results from Phase 1, Phase 2a and preclinical studies of CVT-301, an inhaled form of levodopa, have been featured in the current edition of Science Translational Medicine. Acorda Therapeutics, Inc. (NASDAQ: ACOR) is developing CVT-301 for the treatment of OFF periods in people with Parkinson’s disease (PD).
Introducing Dr. Debra Viertanen
I am a LSVT BIG certified physical therapist offering this program to PWP. I have spent 38 years treating People with Parkinsons and have never found a program that works so well. I also have a certification in hypnotherapy. Many PWP have higher anxiety and difficulty sleeping. I offer hypnosis to assist with this. I will begin another group session Wed, Oct 19 at 1:30 in my office. The sessions take about 45 minutes and are free. There will be 3 in total. PWP and caregivers are welcome. Please call my office to let us know u plan to come. Space is limited. 272-3324. Riverfront Physical Therapy 500 Federal St, Troy
Dr. Debra Virtanen
The triennial World Parkinson Congresses provide an international forum for dialogue on the latest scientific discoveries, medical practices, and caregiver initiatives related to Parkinson’s disease.
Educational Web Pages at https://www.michaeljfox.org/understanding-parkinsons/index.html?navid=understanding-pd
PDF offers a variety of educational publications and programs for people with Parkinson’s, their caregivers and families and allied health professionals. These materials can help answer questions about Parkinson’s disease symptoms, medications, medical care, exercise and nutrition, among other issues.
You can download all materials by using the links below and to the left. You can also order most of these materials online free of charge, for yourself or, in bulk for your practice, hospital or support group.
PDF offers one free educational DVD/video, Diagnosis Parkinson’s Disease: You Are Not Alone. Please click here to read more and order this program online.
PDF’s fact sheets discuss your concerns about nutrition, diet, exercise and more, providing tips on how to improve daily life with Parkinson’s. These are written by physicians and people living with or affected by Parkinson’s. You can order print copies of the fact sheets or download those that interest you from our selection of 35+ fact sheets.
PDF reserves a limited supply of DVDs of our previous series of PD ExpertBriefings for those unable to watch via computer. If you would like to order this set to watch at home or with your support group members, please read more and download our order form.
Parkinson’s disease (PD) is a movement disorder. In people with PD, a vital chemical in the brain called dopamine is gradually reduced. This brings on symptoms of tremor, slowness in movement, stiff limbs, and walking or balance problems.
A helpful article from the MJ Fox foundation
If your muscles often feel stiff and uncomfortable, you’re not alone.
Unique in the world of Parkinson’s resources, the Every Victory Counts® manual gives people living with Parkinson’s – and their caregivers and family members – the tools they need to take control of their own Parkinson’s treatment through a proactive approach to self-care.
Click to read and/or download the book as a PDF file (5mb, 275 page printable book)
These Parkinson’s disease (PD) resources will help you find more information and connect with others living with the condition. Many of these sites will direct you to the latest Parkinson’s disease news and research, as well as opportunities to get involved with local chapters and organizations.
Parkinson’s disease is an unexpected- and unwanted- twist and turn in your life journey. Like any journey there is uncertainty about what lies ahead, how things will change or where your life with PD will take you.
An inhaled form of levodopa is being trialled on Parkinson’s disease patients in a Phase III clinical trial at the University of Nevada School of Medicine.